Movie songs became a specialty, including his signature "Moon River." The longing Johnny Mercer-Henry Mancini ballad was his most famous song, even though he never released it as a single because his record company feared such lines as "my huckleberry friend" were too confusing and old-fashioned for teens.
The song was first performed by Audrey Hepburn in the beloved 1961 film "Breakfast at Tiffany's," but Mancini thought "Moon River" ideal for Williams, who recorded it in "pretty much one take" and also sang it at the 1962 Academy Awards. Although "Moon River" was covered by countless artists and became a hit single for Jerry Butler, Williams made the song his personal brand. In fact, he insisted on it.
"When I hear anybody else sing it, it's all I can to do stop myself from shouting at the television screen, 'No! That's my song!'" Williams wrote in his 2009 memoir titled, fittingly, "Moon River and Me."
"The Andy Williams Show," which lasted in various formats through the 1960s and into 1971, won three Emmys and featured Williams alternately performing his stable of hits and bantering with guest stars.
It was on that show that Williams — who launched his own career as part of an all-brother quartet — introduced the world to another clean-cut act — the original four singing Osmond Brothers of Utah. Their younger sibling Donny also made his debut on Williams' show, in 1963, when he was 6 years old. Four decades later, the Osmonds and Williams would find themselves in close proximity again, sharing Williams' theater in Branson.
Williams did book some rock and soul acts, including the Beach Boys, the Temptations and Smokey Robinson. On one show, in 1970, Williams sang "Heaven Help Us All" with Ray Charles, Mama Cass and a then-little known Elton John, a vision to Williams in his rhinestone glasses and black cape. But Williams liked him and his breakthrough hit "Your Song" enough to record it himself.